Sildenafil citrate is the main active ingredient in Cenforce 50 tablets. The cGMP-specific phosphodiesterase type 5 (PDE5) in the corpus cavernosum, which is situated around the penile, is inhibited by sildenafil.

The active component of Cenforce 50 or silagra 100mg , sildenafil citrate, is located below the PDE 5 enzyme complex and functions by blocking PDE 5, a chemical that reduces cGMP, which is a key role in the treatment of erectile dysfunction. Cenforce prevents PDE5 from attenuating, which results in longer-lasting erections.